Process Chemistry & Process scale-up laboratory
Process development work for the Active Pharmaceutical Ingredients (APIs) is carried out by the Chemical Process Research Laboratory, which focuses on developing commercially viable eco-friendly processes for intermediates and APIs for the regulated global markets. The Labs have capability to handle Pyrophoric reagents.
USVs’ portfolio consists of 51 small molecule APIs with 27 USDMF, 6 CEPs, 22 ASMF (EU), 22 DMF (other markets), 4 JDMF, 8 Korean DMF, 2 China DMF.
Capabilities
- Organic transformations of wide and varied types
- Novel and non-infringing polymorphs
- Classical and dynamic resolutions
- Catalytic hydrogenations
- Heterocyclic chemistry
- Cryogenic chemistry
- Polymer Chemistry
- Green chemistry
- Chiral chemistry
- Biocatalysis
Infrastructure
- 1 to 25 L capacity high pressure SS/Glass/Hastelloy autoclaves
- Parallel synthesizer with colorimetric probe
- Particle size reduction techniques such as Jet milling, Pin milling, Multi milling to obtain particle size below 5 micron
- Preparative scale HPLC
- 2L Autolab system with calorimetry
- Scale-up kilo laboratory to manufacture APIs /Intermediates up to 10 kg
- Drying techniques like Air Tray, Vacuum Tray, Fluidized Bed, spray Dryers and Rotacone Vacuum Dryers